ISOLATION AND IDENTIFICATION OF MAJOR METABOLITE OF ALBUTEROL IN HUMAN URINE
- 1 January 1977
- journal article
- research article
- Vol. 5 (3) , 234-238
Abstract
The major urinary metabolite of albuterol in man was isolated and purified by ion-exchange chromatography and countercurrent distribution. On the basis of PMR, IR and mass-spectral analysis, enzymic hydrolysis, and assay of inorganic sulfate after acid hydrolysis, the metabolite was identified as the 4''-O-sulfate ester of albuterol. [Albuterol is a .beta.-adrenergic bronchodilator used widely as a therapeutic agent in bronchial asthma.].This publication has 4 references indexed in Scilit:
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