Development of a Multiarray Biosensor for DNA Diagnostics
- 1 November 1998
- journal article
- research article
- Published by Taylor & Francis in Instrumentation Science & Technology
- Vol. 26 (5) , 503-514
- https://doi.org/10.1080/10739149808000917
Abstract
This work involves the development and evaluation of a multiarray biosensor for DNA diagnostics. The evaluation of various system components developed for the biosensor is discussed. The DNA probes labeled with visible and near infrared (NIR) dyes are evaluated. The detection system uses a two-dimensional charge-coupled device (CCD). Examples of application of gene probes in DNA hybridization experiments and in biomedical diagnosis (detection of the p53 cancer gene) are presented to illustrate the usefulness and potential of the biosensor device.Keywords
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