DIFFERENCES IN 17-OXOGENIC STEROID EXCRETION IN PREGNANCIES WITH NORMAL AND ANENCEPHALIC FOETUSES

1 January 1973

journal article
Published by Oxford University Press (OUP) in Acta Endocrinologica

Vol. 72 (1) , 156-160
https://doi.org/10.1530/acta.0.0720156

Abstract

The 17-oxogenic steroid excretion of women pregnant with an anencephalic foetus was found to be significantly lower than that of women pregnant with a normal foetus but similar to that of non-pregnant women taking oral contraceptives containing oestrogens. It is suggested that the diminished excretion of 17-oxogenic steroids in pregnancies with an anencephalic foetus may reflect defective production of corticosteroids or their precursors by the abnormal adrenal of the anencephalic foetus.

Keywords

OXOGENIC STEROID
PREGNANCIES
STEROID EXCRETION
ANENCEPHALIC
DEFECTIVE
ADRENAL
ABNORMAL

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