EFFECT OF VITAMIN C DEFICIENCY ON THE DIFFUSION OF T-1824 ACROSS THE CAPILLARY WALL

Publisher Website
Google Scholar
Abstract
The blue dye T-1824 was administered intraven. to 35 scorbutic and 40 normal male guinea pigs. There were no qualitative or quantitative differences in the tissue distribution of the T-1824, except for the extravasation of the dye into the periarticular soft tissue in the scorbutic, but not in the control group. The plasma concn. of T-1824 of scorbutic animals was not significantly different from that of normal guinea pigs of the same age, but was significantly less than that of animals of the same wt. The blood hematocrit was not appreciably altered in scurvy. It was concluded that capillary permeability and blood volume were not altered by vit. C deficiency in the guinea pig.

This publication has 0 references indexed in Scilit: