THE USE OF PIMOZIDE TO POTENTIALIZE THE EFFECTS OF LHRH-A ON PITUITARY GONADOTROPIN-SECRETION - OVULATION AND SPERMIATION IN COMMON CARP (CYPRINUS-CARPIO)
- 1 January 1983
- journal article
- research article
- Vol. 296 (4) , 181-184
Abstract
During the reproductive season in August, an LHRH analog (LHRH-A = D-Trp6EA-LHRH) (50 .mu.g/kg) was administered to adult male and female carp alone or in association with pimozide, a dopamine inhibitor (10 mg/kg). LHRH-A caused the circulating portal level of gonadotropin [GTH] to rise significantly in males and less in females. Spermiation was stimulated in the males and oocyte maturation in females but there was no ovulation. An injection of pimozide and then of LHRH-A 6 h later significantly increased GTH secretion and spermiation more than LHRH-A given alone, and induced ovulation in the females.This publication has 4 references indexed in Scilit:
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