Properties of the R factor R144drd3 inKlebsiella pneumoniaestrain M5a1
- 1 February 1975
- journal article
- research article
- Published by Hindawi Limited in Genetics Research
- Vol. 25 (3) , 327-338
- https://doi.org/10.1017/s0016672300015743
Abstract
SUMMARY: The R factor, R144drd3, mobilized chromosomal genes inKlebsiella pneumoniaestrain M5a1 at similar frequencies to those observed for this R factor inEscherichia coliK12. In a derivativeK. pneumoniaedonor, strain HF3, R144 persisted in the autonomous state but now gave rise to polarized transfer of the chromosome in the order Ohis…arg2…leu…trp. R144drd3 was unstable inK. pneumoniaeM5a1; after successive subculture drug resistance, colicinogeny and transmissibility were lost. In strain HF3, transmissibility was preferentially lost, but determinants for drug resistance, colicinogeny and superinfection immunity were retained; 10–11 copies per chromosome of R144 were present in log phase cultures of both strains.Keywords
This publication has 2 references indexed in Scilit:
- Isolation of Hfr Strains from R + and ColV2 + Strains of Escherichia coli and Derivation of an R′ lac Factor by TransductionJournal of Bacteriology, 1973
- Linkage map of Escherichia coli strain K-12.Microbiology and Molecular Biology Reviews, 1972