Effect of Premedication and General Anaesthesia on Arterial Blood Gases

Abstract
The effect of premedication and general anesthesia was studied in 31 patients. Premedication with atropine or with papaveretum and scopolamine was not followed by a change from the control arterial blood measurements, and in particular there was no change in arterial oxygen saturation or tension, both values being directly measured. Eighteen of the patients underwent carotid angiography under general anesthesia, breathing spontaneously, and no hypoxaemia or other change in the arterial blood measurements occurred in these afterwards, but transient hypoxaemia without hypercapnia was found in 13 patients after other minor operations which required a longer period of anesthesia.