Role of the Enamel Organ in Limiting Fluoride Uptake During the Maturation Phase of Enamel Development

Abstract
Autoradiographs of molar teeth from 15-day-old rats that had been injected with 18F showed no tracer uptake in the late-mineralizing enamel. Autoradiographic and quantitative in vitro experiments indicated that the enamel organ limited fluoride uptake during the maturation phase of enamel formation.