Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells
- 25 October 2002
- journal article
- Published by Springer Nature in Oncogene
- Vol. 21 (50) , 7611-7618
- https://doi.org/10.1038/sj.onc.1206004
Abstract
Oncogene is one of the world’s leading cancer journals. It is published weekly and covers all aspects of the structure and function of Oncogenes. Oncogene also publishes 8 Reviews issues a year, on a broad range of topics.Keywords
This publication has 32 references indexed in Scilit:
- Antiapoptotic protein Bcl-xL is up-regulated during megakaryocytic differentiation of CD34+ progenitors but is absent from senescent megakaryocytesExperimental Hematology, 2001
- Mechanism of STAT3 Activation by Insulin-like Growth Factor I ReceptorJournal of Biological Chemistry, 2000
- Bcl-xL promotes metastasis of breast cancer cells by induction of cytokines resistanceCell Death & Differentiation, 2000
- 17β-Estradiol Inhibits Apoptosis in MCF-7 Cells, Inducing bcl-2 Expression via Two Estrogen-Responsive Elements Present in the Coding SequenceMolecular and Cellular Biology, 2000
- Opposing actions of STAT-1 and STAT-3 on the Bcl-2 and Bcl-x promotersCell Death & Differentiation, 2000
- Bcl-2 with loss of apoptosis allows accumulation of genetic alterations: A pathway to metastatic progression in human breast cancerInternational Journal of Cancer, 2000
- Blockade of the Bcr-Abl Kinase Activity Induces Apoptosis of Chronic Myelogenous Leukemia Cells by Suppressing Signal Transducer and Activator of Transcription 5–Dependent Expression of Bcl-XLThe Journal of Experimental Medicine, 2000
- Erythropoietin Can Induce the Expression of Bcl-xLthrough Stat5 in Erythropoietin-dependent Progenitor Cell LinesJournal of Biological Chemistry, 1999
- Role of epidermal-growth-factor receptor in tumor progression in transformed human mammary epithelial cellsInternational Journal of Cancer, 1998
- An Epidermal Growth Factor Receptor/Jak2 Tyrosine Kinase Domain Chimera Induces Tyrosine Phosphorylation of Stat5 and Transduces a Growth Signal in Hematopoietic CellsPublished by Elsevier ,1996