Changes in lung function between age 8 and 14 years in children with birth weight of less than 1,501 g

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Abstract
We set out to determine whether lung function of children with a birth weight of 1% predicted) at age 8 years mean 88.5% (SD 14.7) and at age 14 years, mean 94.9% (SD 13.8)]. There were significant changes, mostly improvements, in lung function between age 8–14 years relative to predicted values: FEV1 (% predicted) increased between 8–14 years of age by a mean of 6.4 (95% confidence interval, 4.4–8.3). The improvements in some lung function variables were significantly greater in those of birth weight 1 (% predicted) between age 8–14 years in infants with birth weight <1,000 g had a mean of 10.3 (SD 13.1), and in those with birthweight 1,000–1,500 g a mean of 3.3 (SD 10.1). We conclude that lung function improved significantly relative to predicted values in children of birth weight <1,501 g between age 8–14 years. The improvements were greatest in those of birth weight <1,000 g. Pediatr Pulmonol. 1999; 27:185–190.