ROLE OF CENTRAL 5-HYDROXYTRYPTAMINE IN ACUPUNCTURE ANALGESIA

  • 1 January 1979
    • journal article
    • research article
    • Vol. 22  (1) , 91-104
Abstract
The role played by central 5-hydroxytryptamine (5-HT) in acupuncture analgesia (AA) was studied in rats with the tail-flick response as the antinociceptive test. The analgesic effect of acupuncture can be enhanced or lowered by the increment or the decrement of the 5-HT level in the CNS. The turnover rate of 5-HT in the CNS was greatly facilitated during the period of acupuncture. 5-HT in the CNS may be 1 of the most important neurochemical agents mediating AA.