A comparison of transcutaneous bilirubinometers: SpectRx BiliCheck versus Minolta AirShields

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Abstract
Background: Two devices are available for making transcutaneous estimates of serum bilirubin (SBR): the Minolta AirShields JM102 and the new SpectRx BiliCheck. Objectives: (a) To measure how well the readings produced by these devices agree with SBR measured in the laboratory; (b) to estimate for each device, the proportion of infants with clinical jaundice who would require blood sampling if the device was used as a screening tool to detect infants with SBR ≥ 250 μmol/l. Design: Prospective cohort study of jaundiced infants who required SBR at ≤ 20 days of postnatal age. Those who had received phototherapy or exchange transfusion were excluded. Setting: Tertiary neonatal service in South-East Scotland. Interventions: Within 30 minutes of SBR sampling, transcutaneous bilirubinometry was performed using one Minolta and two SpectRx devices (designated A and B). Results: Sixty four neonates were enrolled, 19 of which were preterm (31–35 weeks). The 95% confidence intervals of a device reading corresponding to SBR were ± 66.7, ± 67.9, and ± 66.4 μmol/l respectively. Using the devices to identify all SBR ≥ 250 μmol/l would reduce SBR sampling by 23%, 16%, and 20% respectively. Conclusions: Given that SBR levels range from 50 to 400 μmol/l in jaundiced infants, the 95% confidence intervals of the devices are wide at ± 67 μmol/l. The SpectRx can be used as a screening tool for hyperbilirubinaemia but there is no advantage in using it over the Minolta.