Improved Synthesis of ChiralN-Protected Allylic Amines
- 1 January 1994
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1994 (12) , 1463-1466
- https://doi.org/10.1055/s-1994-25714
Abstract
The α-ester group of N-protected α-amino esters was reduced with diisobutylaluminum hydride to an intermediate aluminoxy acetal that on reaction with a Wittig reagent afforded the title chiral compounds in 48-78% chemical yields.Keywords
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