Effects of ATP and Taurine on Calcium Uptake by Membrane Preparations of the Rat Retina

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Abstract
The effects of ATP and taurine on the kinetics of Ca uptake in rat retinal membrane preparations were determined. ATP increased Ca uptake at low Ca ion concentrations. Addition of ATP plus taurine further increased Ca uptake. Cooperative relationships were observed for Ca uptake in the absence of ATP and taurine. In the presence of phosphate ions reciprocal plots demonstrated upward deflections from linearity, while in the absence of phosphate ions downward deflections were noted. Addition of ATP plus taurine to the incubation system appeared to obliterate the cooperativity. Two uptake systems for Ca were observed.

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