Synthesis of Some Thiazolo[3,2‐b]‐1,2,4‐triazole‐5(6H)‐ones as Potential Platelet Aggregation Inhibitors
- 1 January 1995
- journal article
- research article
- Published by Wiley in Archiv der Pharmazie
- Vol. 328 (2) , 169-173
- https://doi.org/10.1002/ardp.19953280215
Abstract
Twenty new compounds having 2‐methyl‐6‐benzylidenethiazolo[3,2‐b]‐1,2,4‐triazole‐5(6H)‐one (2a–d) and 2‐methyl‐6‐(α‐aminobenzyl)thiazolo‐[3,2‐b]‐1,2,4‐triazole‐5‐ol (5–20) structures were synthesized. Their structures were confirmed by elemental and spectroscopic analysis and their platelet aggregation inhibitory activities were investigated.Keywords
This publication has 8 references indexed in Scilit:
- Bridgehead Nitrogen Heterocycles. Part III. Synthesis of Fused Heterocycles from 3-(2,4-Dichlorophenyl)-5-mercapto-1,2,4-s-triazolesHETEROCYCLES, 1991
- 2,4-Dihydro-3H-1,2,4-triazol-3-ones as anticonvulsant agentsJournal of Medicinal Chemistry, 1990
- Synthesis and biological evaluation of 3-aryloxyalkyl-6-aryl-7H-s-triazolo[3,4-b][1,3,4]thiadiazinesEuropean Journal of Medicinal Chemistry, 1989
- Synthesis of 5-aryl-2H-tetrazoles, 5-aryl-2H-tetrazole-2-acetic acids, and [(4-phenyl-5-aryl-4H-1,2,4-triazol-3-yl)thio]acetic acids as possible superoxide scavengers and antiinflammatory agentsJournal of Medicinal Chemistry, 1984
- Synthesis and pharmacology of novel anxiolytic agents derived from 2-[(dialkylamino)methyl-4H-triazol-4-yl]benzophenones and related heterocyclic benzophenonesJournal of Medicinal Chemistry, 1976
- Antituberculosis agents—ITetrahedron, 1970
- The Addition of Secondary Amines to Some α-Benzal KetonesJournal of the American Chemical Society, 1955
- The Preparation of Heterocyclic Sulfonamides1Journal of the American Chemical Society, 1950