The induction of gene mutation and chromosome aberration inChlamydomonas eugametosby a phenylalanine analog

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Abstract
Evidence is presented which indicates that the phenylalanine analog 2-amino-3-phenylbutanoic acid (APBA) induces mutation to APBA, streptomycin, and neamine resistance in the green alga Chlamydomonas eugametos. Apparent chromosome abnormalities (reciprocal translocations and inversions) were also found among some clones recovered after APBA treatment. The two, mutation and chromosome aberration, are separable.