Role of the Transmembrane Domain and Flanking Amino Acids in Internalization and Down-regulation of the Insulin Receptor

This publication has 31 references indexed in Scilit:

• The insulin signaling system.
  Journal of Biological Chemistry, 1994
• IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85.
  Proceedings of the National Academy of Sciences, 1992
• The insulin receptor juxtamembrane region contains two independent tyrosine/beta-turn internalization signals.
  The Journal of cell biology, 1992
• Insulin-induced surface redistribution regulates internalization of the insulin receptor and requires its autophosphorylation.
  Proceedings of the National Academy of Sciences, 1992
• Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein
  Nature, 1991
• The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling
  Cell, 1985
• Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes
  Nature, 1985
• Electrophoretic resolution of three major insulin receptor structures with unique subunit stoichiometries.
  Proceedings of the National Academy of Sciences, 1980
• Intracellular Translocation of Iodine-125-Labeled Insulin: Direct Demonstration in Isolated Hepatocytes
  Science, 1978
• 125I-insulin binding to cultured human lymphocytes. Initial localization and fate of hormone determined by quantitative electron microscopic autoradiography.
  Journal of Clinical Investigation, 1978