PRICK- AND RADIOALLERGSORBENT TESTS (RAST) TO ALCALASE® IN A POPULATION NOT EXPOSED TO ENZYME DETERGENTS

Abstract
A total of 301 persons in a population unexposed to enzyme detergents (Rumania) were prick-tested with Alcalase, and RASTs were performed on their sera. The material consisted of three groups, one atopic, the second non atopic, and the third healthy. In the first two groups the percentage of positive prick-test reactions amounted to 6 and 5% respectively. Only one positive RAST was found (second group). In the third group no positive prick-tests were found and no positive RASTs. The majority of the positive prick-tests were considered non specific, and no correlation was found between results of prick-tests and RASTs in this material of non exposed individuals.