Determination of Bisphenol A in Water by Micro Liquid--Liquid Extraction Followed by Silylation and Gas Chromatography--Mass Spectrometry Analysis
Open Access
- 1 November 1998
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Chromatographic Science
- Vol. 36 (11) , 565-570
- https://doi.org/10.1093/chromsci/36.11.565
Abstract
A method for the determination of bisphenol A according to the European Union guideline, which establishes a limit of 0.1 ng/mL for organic pollutants in water, is proposed. The method involves a micro liquid—liquid extraction using dichloromethane followed by a silylation step. Identification and quantitation are performed with gas chromatography—mass spectrometry, using an HP-5MS column. The retention time is 7.02 min. Quantitation is carried out using single-ion monitoring (SIM) at m/z 73, 357, and 372. A clean-up is not necessary using SIM mode. Deuterated anthracene (2H10-anthracene) is used as an internal standard. The method is applied to the determination of bisphenol A at very low concentration levels (10.0–250.0 ng/L) in different types of natural water samples. The detection limit obtained is 0.4 ng/L. Recovery efficiencies are close to 100% in all cases.Keywords
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