Hypophosphataemic Rickets
- 1 August 2000
- journal article
- review article
- Published by S. Karger AG in Hormone Research in Paediatrics
- Vol. 53 (Suppl. 3) , 57-60
- https://doi.org/10.1159/000023535
Abstract
X-Linked hypophosphataemic rickets (XLH) is frequently associated with short stature even when conventional treatment (1,25-dihydroxyvitamin D3 or 1α-hydroxyvitamin D3 plus inorganic phosphate salts) is administered for a long time. The pathogenesis of growth retardation is probably multifactorial. Affected patients usually show normal growth hormone (GH) secretion. In some poorly growing XLH patients, long-term GH treatment associated with conventional therapy improves linear growth. GH treatment also increases phosphate retention but this effect is transient.Keywords
This publication has 2 references indexed in Scilit:
- Genetic causes of ricketsCurrent Opinion in Pediatrics, 1999
- Effects of calcitriol and phosphorus therapy on the growth of patients with X-linked hypophosphatemiaJournal of Clinical Endocrinology & Metabolism, 1993