Effect of 2,4‐dinitrofluorobenzene on the enzymatic properties of the b‐c1 complex isolated from beef heart mitochondria
Open Access
- 20 January 1986
- journal article
- Published by Wiley in FEBS Letters
- Vol. 195 (1-2) , 298-302
- https://doi.org/10.1016/0014-5793(86)80181-8
Abstract
A study is presented on the effect of 2,4‐dinitrofluorobenzene (DFNB) on the enzymatic properties of mitochondrial b‐c 1 complex. The chemical modification by DNFB strongly inhibits the reductase activity of the complex, this being accompanied by labelling by [3H]DNFB of core protein I, the apoprotein of b cytochromes and the 12 kDa subunit. Chemical modification by DNFB appears to alter, in particular, the domain of heme b‐562.Keywords
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