Function of chitin oligosaccharides in plant and animal development

Abstract
In plant development chitin oligosaccharides have been studied intensively as part of the communication between leguminous plants and Rhizobium bacteria. The Rhizobium bacteria synthesize and secrete lipochitin oligosaccharides (LCOs) to induce the development of a root nodule, in which the bacteria will infiltrate to start a symbiotic relation with the plant. Here we will give an overview of the biosynthetic route used by the bacteria to synthesize these LCOs. Perception by the plant will also be discussed as well as early responses to the LCOs. By working with the genes from the biosynthetic route, other genes were identified that share homology with the chitin synthase genes from Rhizobium. These genes are now isolated from human, mouse, chick, Xenopus and zebrafish and can be divided into three classes. They are mainly expressed during early development at the same stage as chitin oligosaccharide synthase activity can be detected. A controversy has been risen about their biochemical activity and will be further discussed here.

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