Observations on the Interrelationships of Intracranial Pressure and Cerebral Blood Flow

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Abstract
The rate of intracranial blood flow is a principal variable controlling the intracranial pressure of rhesus monkeys. It is through alterations in the rate of cerebral flow that changes in arterial blood pressure and cardiac output influence intracranial pressure. The authors suggest that chemically or reflexly induced increases in intracranial pressure are due to an increase in cerebral flow secondary to changes in cerebral arteriolar resistance or pres- sure.