Amphotericin B Lipid Complex in the Management of Invasive Aspergillosis in Immunocompromised Patients
Open Access
- 1 May 2005
- journal article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 40 (Supplement) , S392-S400
- https://doi.org/10.1086/429333
Abstract
Invasive fungal infections are a serious concern in immunocompromised patients, and the types of pathogens seen in patients have shifted over time. Groll et al. [1] documented the changing patterns in pathogens responsible for invasive fungal infections from the late 1970s to the early 1990s at a German university hospital. The overall prevalence of invasive fungal infections identified at autopsy increased from 2% during 1978–1982 to 7% in 1992 [1]. During 1978–1982, Candida species were the most commonly isolated fungal pathogens at autopsy, but, during 1988–1992, Aspergillus species were detected most frequently, suggesting that mortality due to aspergillosis was increasing.Keywords
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