CONDITIONING BY CORTICOIDS FOR THE PRODUCTION OF CARDIAC LESIONS WITH NORADRENALINE
- 1 February 1959
- journal article
- research article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 30 (2) , 183-187
- https://doi.org/10.1530/acta.0.0300183
Abstract
Intact and adrenalectomized rats treated for 10 days with a daily dose of 500 [mu]g4[DELTA]1,4-pregnadiene-3,20-dione-9[alpha]-fluoro-11[beta], 16[alpha],17[alpha]21-tetrol, 3 mg desoxycorticosterone acetate and 250 [mu]g norepinephrine administered on the 8th and 9th days only develop a diffuse type of myocardial lesion resembling the spotty myolysis lesion of man.Keywords
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