The long‐term effects of auto‐immunologically induced granulomas on the testes of rainbowtrout, Salmo gairdneri Richardson

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Abstract
Complex giant cell granulomas were induced within the testis of mature rainbow trout following immunization with testis in Freund's complete adjuvant. Although such granulomas could completely fill the seminiferous tubules and sperm duct, they had no inhibitory effect on spermato‐genesis during a subsequent maturation. Germ cells developed normally around the periphery of the granulomas. The spermatozoa produced, however, were often prevented from being released by the presence of these long‐term granulomas within the sperm duct.