PERFUSION I131 MACROAGGREGATE BRAIN SCANNING; A CLINICAL EVALUATION OF ITS DIAGNOSTIC EFFICIENCY

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Abstract
We have endeavored to make a clinical evaluation of perfusion scanning in a study of 50 patients with various types of intracranial pathology. Several recent articles in the medical literature have pointed to the innocuous nature of this process insofar as the presence of the microemboli is concerned. The difference inherent is this type of brain scanning and its potential importance lie in the fact that it delineates cerebral blood flow only where this is preserved. Under the most rigid conditions of safety, we injected 50 microcuries of the I131 radioactive tracer into the internal carotid artery, usually under roentgenologic control, at the end of the angiographic study. The patients were seen in the National Institute of Neurology and the injection was carried out under local or general anesthesia. The radioactive substance, diluted in 5 ml. of isotonic saline solution, was injected on the side corresponding to the suspected lesion. Lateral and anteroposterior scannings were made. In the body of this paper we have discussed the generally excellent correlation between the scan and clinical findings, the variety of lesions which it can localize without, however, supplying us with data which could suggest the pathologic nature of the lesion, and finally, the added proofs that the microemboli in themselves do not damage the brain tissue.

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