Abstract
A person's maximal bone density — termed the peak bone mass — is usually achieved in the third decade of life; thereafter, bone is inexorably lost. Many of the unanswered questions that currently limit our understanding of osteoporosis concern the gain and subsequent loss of bone mass. Deciphering the complex network of factors that determine peak bone mass may be the key to preventing osteoporosis.For some physiologic variations, such as the range of the serum sodium concentration, persons with values at the lower end of the normal range are no less healthy than those with values at the upper . . .