BUPRENORPHINE (TEMGESIC) AS A PEROPERATIVE ANALGESIC - A DOUBLE CENTER STUDY

  • 1 January 1983
    • journal article
    • research article
    • Vol. 32  (2) , 75-79
Abstract
Using buprenophrine as the sole i.v. analgesic in balanced anesthesia, the most suitable dose of buprenorphine, was found and compared to fentanyl, regarding analgesic, circulatory and side effects. Initial doses of 5, 10 and 15 .mu.g/kg buprenorphine and 10 .mu.g/kg fentanyl were compared. Peroperative analgesia was adequate with both drugs and neither gave circulatory effects of clinical significance. After buprenorphine, 3 of 60 patients and after fentanyl 5 of 11 patients were given naloxone. Nausea was more common after buprenorphine. Postoperative analgesia after the last dose of buprenorphine averaged 13 h, significantly longer than the 2 h after fentanyl. The overall course was considered good in 93% of buprenorphine and 100% of fentanyl cases. Buprenorphine doses are discussed.

This publication has 1 reference indexed in Scilit: