Failure of autologous stem cell transplantation in refractory thrombocytopenic purpura
- 1 October 1998
- journal article
- case report
- Published by Springer Nature in Bone Marrow Transplantation
- Vol. 22 (8) , 827-828
- https://doi.org/10.1038/sj.bmt.1701431
Abstract
A 44-year-old man with splenectomised refractory autoimmune thrombocytopenic purpura (AITP) of 10 years' duration underwent an autologous, T cell-depleted marrow transplant following conditioning with thiotepa and CY. There was no response to the transplant procedure. This is the fourth case in the literature to show failure following autologous stem cell transplantation, although complete, steroid-independent remissions were obtained in the first two patients for over 1 year.Keywords
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