Effect of Adrenalectomy on the Pancreas of db/db Mice
- 1 November 1986
- journal article
- research article
- Published by Georg Thieme Verlag KG in Hormone and Metabolic Research
- Vol. 18 (11) , 743-745
- https://doi.org/10.1055/s-2007-1012424
Abstract
Adrenalectomy has been performed in the diabetic mouse and the islet immunohistochemistry studied. Adrenalectomy restored blood glucose to normal. Mean islet size of diabetic animals was larger than that of either adrenalectomized diabetic animals or of lean controls. Adrenalectomy restored the immunohistochemical appearance of the islets to normal when examinded with anti-insulin, anti-glucagon and anti-somatostatin antisera.Keywords
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