Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context

This publication has 30 references indexed in Scilit:

• Targeting RAS signalling pathways in cancer therapy
  Nature Reviews Cancer, 2003
• Identification of a Candidate Tumor-Suppressor Gene Specifically Activated during Ras-Induced Senescence
  Experimental Cell Research, 2002
• The Guanine Nucleotide-Binding Switch in Three Dimensions
  Science, 2001
• Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a
  Cell, 1997
• Acre-transgenic mouse strain for the ubiquitous deletion ofloxP-flanked gene segments including deletion in germ cells
  Nucleic Acids Research, 1995
• Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
  Cell, 1994
• Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.
  Proceedings of the National Academy of Sciences, 1993
• Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice.
  Genes & Development, 1991
• Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes
  Published by Elsevier ,1988
• Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture
  Nature, 1983