PCSK9: An enigmatic protease

This publication has 80 references indexed in Scilit:

• The self-inhibited structure of full-length PCSK9 at 1.9 Å reveals structural homology with resistin within the C-terminal domain
  Proceedings of the National Academy of Sciences, 2007
• Secreted PCSK9 promotes LDL receptor degradation independently of proteolytic activity
  Biochemical Journal, 2007
• The Cellular Trafficking of the Secretory Proprotein Convertase PCSK9 and Its Dependence on the LDLR
  Traffic, 2007
• Molecular Characterization of Loss-of-Function Mutations in PCSK9 and Identification of a Compound Heterozygote
  American Journal of Human Genetics, 2006
• Genetic causes of familial hypercholesterolaemia in patients in the UK: relation to plasma lipid levels and coronary heart disease risk
  Journal of Medical Genetics, 2006
• Sequence Variations inPCSK9,Low LDL, and Protection against Coronary Heart Disease
  New England Journal of Medicine, 2006
• Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotype
  Proceedings of the National Academy of Sciences, 2004
• Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes
  Proceedings of the National Academy of Sciences, 2003
• Mutations in PCSK9 cause autosomal dominant hypercholesterolemia
  Nature Genetics, 2003
• The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): Liver regeneration and neuronal differentiation
  Proceedings of the National Academy of Sciences, 2003