Borna disease virus RNA in peripheral blood mononuclear cells obtained from healthy dairy cattle
- 12 December 1996
- journal article
- Published by Springer Nature in Medical Microbiology and Immunology
- Vol. 185 (3) , 145-151
- https://doi.org/10.1007/s004300050024
Abstract
We examined natural infection of Borna disease virus (BDV) in 74 healthy dairy cattle in Japan. The seroprevalence determined using recombinant BDV p24 protein was 20.3%. The prevalence of BDV RNA in peripheral blood mononuclear cells (PBMCs) determined by polymerase chain reaction for p24 was 10.8%. Cell fraction of the PBMCs revealed the presence of BDV RNA in the T cell-enriched fraction. Thus, BDV infection is wide-spread even among healthy cattle.Keywords
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