Stereocontrolled Total Synthesis of (5Z,8Z,10E,12R,14Z)-12-Hydroxy-5,8,10,14-icosatetraenoic Acid [(12R)-HETE]
- 1 January 1989
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1989 (12) , 898-901
- https://doi.org/10.1055/s-1989-27425
Abstract
A stereocontrolled convergent synthesis of (12R)-HETE (1) by palladium (0)/thallium hydroxide mediated coupling of vinylborane 2 with the vinyl iodide 3 is reported.Keywords
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