Ontogenetic study of a myelin-derived fraction with 2′:3′-cyclic nucleotide 3′-phosphodydrolase activity higher than that of myelin
- 1 November 1975
- journal article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 151 (2) , 435-437
- https://doi.org/10.1042/bj1510435
Abstract
A membrane fraction (SN 4), prepared from developing and mature rat forebrain by hypo-osmotic treatment of microsome (microsomal-fraction)-free myelin, appears to be closely related to the myelin-like fraction. Fraction SN 4 shows 2′:3′-cyclic nucleotide 3′-phosphohydrolase activity higher than that of the parent myelin. Electrophoresis reveals a multitude of bands with the Wolfgram protein as the main component.Keywords
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