Trypsin Protein Esterase in Relation to Ozone-Induced Vascular Damage

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Abstract
A longitudinal study of the serum trypsin protein esterase of rabbits exposed to 0.4 ppm of ozone for a calendar period of ten months showed that its concentration was slowly but steadily rising. After the animals were killed, microscopic examinations revealed that the wails of the small pulmonary arteries were thickened. It is inferred that the gradual rise of serum trypsin protein esterase values may have reflected this chronic process. The simple esterase method can serve as a substitute for the quantitative determination of the α2-macroglobulin in serum.

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