Investigation of changes in the lipid content of guinea-pig lung after anaphylaxis

1 April 1975

journal article
Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology

Vol. 27 (4) , 248-253
https://doi.org/10.1111/j.2042-7158.1975.tb10694.x

Abstract

A detailed analysis of the lipid content of guinea-pig lung following anaphylaxis in vivo induced by aerosolized antigen snowed a significant reduction in all fractions. Anoxia induced by nitrogen produced reductions in the partial glycerides and ethanolamine phospholipid. Exposure to an aerosol of histamine caused a reduction in all but the choline phospholipid and sphingolipid fractions. It was concluded that the losses of choline phospholipid and sphingolipid result from the anaphylactic reaction and not from subsequent changes.

Keywords

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