New Scintigraphic Method for the Quantitative Measurement of Enterogastric Reflux

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Abstract
A modified, quantitative cholescintigraphic method for the assessment of enterogastric reflux was developed. The distribution of the hepatobiliary tracer 99mTc-Hida is continuously recorded by a computer for 1 h after i.v., injection of the substance. With the patient still in a supine position under the .gamma. camera 2 administrations were made orally; a gelatin capsule containing a known amount of 99mTc-pertechnetate, which was studied, making possible a determination of the relation between registered counts and known activity; and 99mTc-labeled Albu-Res in water, which identified the gastric region. An i.v., injection of synthetic cholecystokinin (Kinevac) 25 min after Hida administration emptied the biliary system into the duodenum in a controllable manner. The lower limit of reflux detected by this method was about 0.5% of the Hida dose given.