VASCULAR ALTERATIONS IN DELAYED RADIATION NECROSIS OF BRAIN

  • 1 January 1976
    • journal article
    • research article
    • Vol. 100  (10) , 531-534
Abstract
A 51 yr old woman given cobalt therapy for nasopharyngeal carcinoma was seen 3 yr later with a mass in the left frontotemporal region of the brain. Biopsy specimen of the lesion showed the classic features of delayed radiation necrosis on light microscopy. Several blood vessels showed endothelial cell proliferation. Transmission electron microscopical study demonstrated numerous alterations of the endothelial cell, such as intraluminal infoldings of the plasma membrane, an increased amount of cytoplasmic organelles, the frequent occurrence of tubular bodies, and degenerative and reactive changes in the neuropil.

This publication has 0 references indexed in Scilit: