Some Aspects of Erythropoietic Cell Proliferation in Erythroleukaemia

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Abstract
Cytophotometric-autoradiographic investigations on erythropoiesis in erythroleukaemia indicate: (1) the decreased labelling index of erythroblasts is explained by an increased percentage of these cells in G1;(2) ‘megaloblastoid’ basophilic erythroblasts show a more pronounced decrease of their fraction in DNA synthesis than morphological normal cells; (3) ‘megaloblastoid’ early polychromatic normoblasts represent a non-proliferating cell population, and (4) the detected disturbance of cell proliferation – eventhough temporary – can bereversed.

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