Reappraisal of the quantitative importance of non-skeletal-muscle source of Nτ-methylhistidine in urine
- 15 March 1981
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 194 (3) , 1011-1014
- https://doi.org/10.1042/bj1941011
Abstract
The claim of Millward, Bates, Grimble, Brown, Nathan & Rennie [(1980) Biochem. J. 190. 225–228] that muscle actomyosin contributes as little as 25% of urinary N tau-methylhistidine is not consistent with other published data from that group [Bates, DeCoster, Grimble, Holloszy, Millward & Rennie (1980) J. Physiol. (London) 303, 41 P] or with literature values. It appears likely that the turnover rate of muscle actomyosin has been considerably underestimated and that when realistic rates of protein turnover are used, muscle tissue remains the major contributor of N tau-methylhistidine in urine.This publication has 12 references indexed in Scilit:
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