Preoperative Autologous Donation Decreases Allogeneic Transfusion but Increases Exposure to All Red Blood Cell TransfusionResults of a Meta-analysis

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Abstract
CONCERN about the transmission of hepatitis and human immunodeficiency virus with allogeneic red blood cell transfusion has led to an increase in the use of measures aimed to reduce perioperative exposure to allogeneic blood. Of the many alternatives available, including cell salvage,1 intraoperative hemodilution,2 and medications such as aprotinin,3 tranexamic acid,4 and erythropoietin,5 preoperative autologous donation of blood is one of the most widely used methods.