The Isolation of Two New Fungal Inhibitors of35S-TBPS Binding to the Brain GABAA/benzodiazepine chloride Channel Receptor Complex
- 1 June 1994
- journal article
- research article
- Published by Taylor & Francis in Natural Product Letters
- Vol. 4 (3) , 171-178
- https://doi.org/10.1080/10575639408043901
Abstract
Bioassay-guided fractionation of the ethyl acetate extracts of the culture filtrate of the fungal culture HA 137–89 yielded the two salicylic acid derivatives 1 and 2, as inhibitors of the binding of 35S-TBPS to the GABAA/benzodiazepine chloride channel receptor complex in vitro. Their structures were determined by spectroscopic and chemical methods.Keywords
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