Genetic engineering of a recombinant fusion possessing anti-tumor F(ab′)2 and tumor necrosis factor
- 28 February 1997
- journal article
- Published by Elsevier in Journal of Biotechnology
- Vol. 53 (1) , 3-12
- https://doi.org/10.1016/s0168-1656(96)01639-2
Abstract
No abstract availableKeywords
This publication has 10 references indexed in Scilit:
- A genetically engineered single-chain FVTNF molecule possesses the anti-tumor immunoreactivity of FV as well as the cytotoxic activity of tumor necrosis factorMolecular Immunology, 1995
- A recombinant antibody-interleukin 2 fusion protein suppresses growth of hepatic human neuroblastoma metastases in severe combined immunodeficiency mice.Proceedings of the National Academy of Sciences, 1994
- Comparative biological properties of a recombinant chimeric anti-carcinoma mAb and a recombinant aglycosylated variantCancer Immunology, Immunotherapy, 1992
- Production of murine V-human cr1 chimeric anti-tag72 antibody using V region cdna amplified by PCRMolecular Immunology, 1990
- Phase I study of recombinant human tumor necrosis factor ? in advanced malignant diseaseCancer Immunology, Immunotherapy, 1989
- Recombinant Human Tumor Necrosis Factor Administered as a 24-Hour Intravenous Infusion. A Phase I and Pharmacologic StudyJNCI Journal of the National Cancer Institute, 1988
- Genetically engineered immunoglobulins reveal structural features controlling segmental flexibility.Proceedings of the National Academy of Sciences, 1988
- Recombinant human tumor necrosis factor administered as a five-day continuous infusion in cancer patients: phase I toxicity and effects on lipid metabolism.Journal of Clinical Oncology, 1988
- Phase I clinical trial of recombinant human tumor necrosis factorCancer Chemotherapy and Pharmacology, 1987
- A monoclonal antibody-Pseudomonas toxin conjugate that specifically kills multidrug-resistant cells.Proceedings of the National Academy of Sciences, 1987