Measurement of fibrinogen-fibrin-related antigen in serum as aid to diagnosis of deep vein thrombosis in outpatients.
- 15 February 1975
- Vol. 1 (5954) , 367-369
- https://doi.org/10.1136/bmj.1.5954.367
Abstract
A study of serum levels of fibrinogen-fibrin-related antigen (F.R.-antigen) in outpatients presenting with clinical features suggesting deep vein thrombosis was undertaken. A raised serum level of this antigen (greater than 12 mg/1) is strong evidence in favour of the diagnosis of deep vein thrombosis. It is virtually conclusive evidence if other known causes of a raised level of the antigen are absent. On the other hand, a normal serum level of F.R.-antigen does not exclude even extensive thrombosis, and other objective techniques are required to substantiate the diagnosis.Keywords
This publication has 12 references indexed in Scilit:
- Fibrin Split Products in Acute Pulmonary EmbolismAnnals of Internal Medicine, 1973
- The Laboratory Diagnosis of Venous Thromboembolic Disease by Measurement of Fibrinogen/Fibrin Degradation Products and Fibrin MonomerChest, 1973
- Prognostic value of serum fibrinogen-related antigen levels after myocardial infarction.Heart, 1973
- ASSOCIATION OF FIBRINOGEN-FIBRINRELATED ANTIGEN (F.R.-ANTIGEN) WITH POSTOPERATIVE DEEP-VEIN THROMBOSIS AND SYSTEMIC COMPLICATIONSThe Lancet, 1972
- Spontaneous fibrinolysis in pulmonary embolismJournal of Clinical Investigation, 1971
- 16. DETECTION OF FIBRIN(OGEN) DEGRADATION PRODUCTS BY A LATEX CLUMPING METHODScandinavian Journal of Haematology, 1971
- Serum Fibrin/Fibrinogen Degradation Products Associated with Postoperative Pulmonary Embolus and Venous ThrombosisBMJ, 1970
- 125I-LABELLED FIBRINOGEN TEST ADAPTED FOR ROUTINE SCREENING FOR DEEP-VEIN THROMBOSISThe Lancet, 1970
- DETECTION OF VENOUS THROMBOSIS IN THE LEGSThe Lancet, 1965
- An Immunological Method for Demonstrating Fibrin Degradation Products in Serum and its Use in the Diagnosis of Fibrinolytic StatesBritish Journal of Haematology, 1963