Neuroblastoma

Abstract
NEUROBLASTOMA and its variant ganglioneuroblastoma is the second most common solid malignant tumor of infants and children; the frequency of its occurrence is exceeded only by tumors of the central nervous system.1 These tumors arise from cells derived from embryonic sympathetic neuroblasts and thus may originate in the adrenal gland or sympathetic ganglions of the cervical, posterior mediastinal, retroperitoneal and abdominal regions.2 Tumors have been reported in unusual locations such as the bladder, lip and sciatic nerve.3 , 4 Primary Central-nervous-system neuroblastoma is also rare, though involvement of the spinal cord secondary to growth through neural foramens is not uncommon.Before 1941 . . .

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