Inhibitors of Protein Tyrosine Kinase pp60v-src: Sterol Sulfates from the Brittle Star Ophiarachna incrassata
- 1 November 1994
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 57 (11) , 1591-1594
- https://doi.org/10.1021/np50113a023
Abstract
Bioactivity-guided fractionation of the extracts of the green brittle star Ophiarachna incrassata using a protein tyrosine kinase pp60v-src inhibition assay led to the isolation of a new sterol sulfate [2] together with four known ones (1,3-5). All five compounds were found to inhibit protein tyrosine kinase pp 60v-src.Keywords
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