The Neuromuscular Mechanism of Alkalotic and Hypocalcemic Tetany.

Publisher Website
Google Scholar
Abstract
Tetany was produced acutely in 11 cats and one dog with solns. of NaHCO3, Na2CO3 and a phosphate buffer administered by venoclysis. Fasciculations and tonic spasms involving especially the head and forelimb musculature characterized this form of tetany. Clonic spasms were not seen in anesthetized animals. Section of the hypoglossal nerve did not significantly influence the fasciculations of the tongue musculature. Section of the brachial plexus did not significantly influence the fasciculations or tonic spasms of the forelimb musculature. Paralytic doses of d-tubocurarine blocked all motor manifestations of tetany. It was concluded that all of the motor phenomena characterizing alkalotic and hypocalcemic tetany could result from the spontaneous iterative dischatges occurring in peripheral motot nerve fibers or their terminations.
Keywords

This publication has 5 references indexed in Scilit: