N-ACETYL-BETA-GLUCOSAMINIDASE IN LYMPHOCYTES OF PATIENTS WITH HODGKINS-DISEASE, PLASMA-CELL MYELOMA AND PRIMARY POLYCYTHEMIA

  • 1 January 1976
    • journal article
    • research article
    • Vol. 14  (4) , 285-289
Abstract
The N-acetyl-.beta.-glucosaminidase activity was cytochemically determined in the peripheral blood lymphocytes of 10 patients with Hodgkin''s disease, 10 with plasma cell myeloma and 10 with primary polycythemia as well as in 20 healthy controls. In all patients studied a significant decrease in the enzyme-positive cell count with a decrease of the intracellular content of enzyme-positive lysosomal granules was noted. These alterations were more marked in patients with Hodgkin''s disease.

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